Abstract

ESQUIVEL-LUNA, Jeremy; ZELADA-RIOS, Laura  and  BEJARANO-FERREYRA, José. Cryptococcal meningitis in a patient with idiopathic CD4+ T lymphopenia. Acta méd. Peru [online]. 2021, vol.38, n.2, pp.139-144. ISSN 1728-5917.  http://dx.doi.org/10.35663/amp.2021.382.2123.

Infection with the human immunodeficiency virus (HIV) is the main risk factor for developing cryptococcal meningitis. However, there is a poorly known entity, idiopathic CD4+ T-cell lymphopenia, which leads to an unexplainable CD4+ circulating T-cell deficit, predisposing patients to many complications, including infections caused by opportunistic microorganisms. We present the case of a patient with cryptococcal meningitis secondary to idiopathic T-CD4+ lymphopenia, which, as far as we know, is the very first case of its kind reported in Peru. This entity should be considered in patients negative for HIV infection developing non-common infections of the central nervous system, since outcome, management, and prognosis may be different in patients with this condition.

Keywords : Meningitis, Cryptococcal; T-Lymphocytopenia, Idiopathic CD4-Positive Lymphopenia; Immunologic Deficiency Syndromes; HIV; Perú.

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