Revista de la Sociedad Química del Perú
versión impresa ISSN 1810-634X
Compounds with substructures like CF 3 -C=C-NH-R are remarkable reactive towards primary amines. They behave like "ortho-fluorides" and are readily susceptible to elimination / addition sequences which can be linked together and performed as domino reactions.
Palabras llave : 5-Fluoro-4-trifluoromethyl-1,3-azoles; 5-azido-4-trifluoromethyl-1,3-azoles; 5-amino-4-trifluoromethyl-1,3-azoles; domino reaction; [1.4] HF-elimination; Michael addition.