Abstract

BHUSHAN TEWARI, Brij  and  SINGH, Shivanand. Studies on medical applications of natural antifungals - metal hexacyanoferrate(ii) complexes. Rev. Soc. Quím. Perú [online]. 2006, vol.72, n.4, pp.197-204. ISSN 1810-634X.

Copper, mercury, molybdenum and zinc ferrocyanides were synthesized and characterized by elemental and spectral studies. The natural antifungal plants extract were collected from Cassia alata (Canicro bush), Azadirachta indica (Neem), Ocimum sanctum (Tulsi) and Cassia obtusifolia (Money bush). Antifungal activity of natural antifungals, metal ferrocyanides and natural antifungal-metal ferrocyanide complexes were tested by well known cultured fungus (Aspergillus niger). The natural antifungals with metal ferrocyanides complexes were found to be have more antifungal property in comparison to metal ferrocyanides and natural antifungals alone. The mercury ferrocyanide with Neem and copper ferrocyanide with Canicro bush complexes were found to have highest and lowest antifungal properties, respectively.

Keywords : natural antifungal; metal hexacyanferrate(II)complex; medical applications; Aspergillus niger; skin infections.