Abstract

HORMAZA, Angelina  and  ARBELAEZ PEREZ, Oscar Felipe. Synthesis of a new serie of pyrrole via cycloaddition. Rev. Soc. Quím. Perú [online]. 2009, vol.75, n.1, pp.12-16. ISSN 1810-634X.

Through the concerted 1,3-dipolar cycloaddition mechanism and in basic and anhydrous conditions a new series of derivatives pyrroles was synthesized of α,β-unsaturated carbonylic compounds (chalcones) and the nitrogenated synthon Tosylmethylisocianide (TOSMIC). The starting materials, α,β-unsaturated carbonylic compounds, were obtained through Claisen-Schmidt condensation from the respective acetophenones and benzaldehydes substituted in meta position; the TOSMIC is a precursor commercially available. The spectroscopic characterization of both the precursor of the target molecules was perfonned using the conventional techniques as nuclear magnetic resonance (¹H- y ¹³C-RMN) and infrared spectroscopy.

Keywords : Pyrrole; ,-unsaturated carbonylic compounds; TOSMIC.

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