Abstract

ENCISO GUTIERREZ, Javier et al. Antioxidant activity of hydroalcoholic extract of medicinal plants and stimulation of fibroblast proliferation. Rev. Soc. Quím. Perú [online]. 2010, vol.76, n.1, pp.73-79. ISSN 1810-634X.

The objective of this work was to evaluate the effect of hydro alcoholic plant extracts: Bixa orellana (achiote), Eupatorium triplenerve (asmachilca), Physalis peruviana (aguaymanto) and Equisetum arvense (cola de caballo) on the proliferation of primary cultures of fibroblasts. We also evaluated the antioxidant capacity, polyphenol and flavonoid contents of the plant extracts. Our results showed that Bixa orellana and Physalis peruviana had the highest antioxidant capacity, Bixa orellana had the highest concentrations of polyphenols and flavonoids. All the plant extracts stimulated differentially the proliferation of fibroblasts, however, Equisetum arvense had the highest stimulation but the lowest antioxidant activity, polyphenol and flavonoid contents. On the other hand, Bixa orellana and Physalis peruviana had moderately effect on the proliferation of fibroblasts, and Eupatorium triplenerve had the lowest effect.

Keywords : fibroblasts; proliferation; antioxidants; medicinal plants.

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