Abstract

FUERTES R., César M., BENAVIDES, Angelyne, PIZZA, Cosimo et al. Analytical chemical study of alkaloyd fraction of methanolic extract of Croton baillonianus (AUBL) leaves. Rev. Soc. Quím. Perú, Apr./Jun. 2012, vol.78, no.2, p.138-143. ISSN 1810-634X.

The objective of the present study has been to extract and isolate the alkaloids from leaves of Croton baillonianus, corresponding to the methanolic extract by exclusion chromatography with Sephadex LH-20 followed by a purification by high performance liquid chromatography, obtaining six alkaloids. Two low polarity alkaloid and two glycoside alkaloids were analyzed by Electronic System impact mass spectrometry; these alkaloids belong to bencylisoquinolinic type; the study has connection to the determination of its antioxidant, antiulcerose and citotoxic properties.

Keywords: Sephadex; alkaloids; exclusion chromatography; mass spectrometry; electron system impact.