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Revista de la Sociedad Química del Perú
versión impresa ISSN 1810-634X
Resumen
DOROTEO, Víctor Hugo et al. Phenolic compounds and antioxidant, antielastase, anticollagenase and photoprotective in vitro activities of Myrciaria dubia (camu camu) and Caesalpinia spinosa (tara). Rev. Soc. Quím. Perú [online]. 2012, vol.78, n.4, pp.254-263. ISSN 1810-634X.
In order to explore the potential of tara (Caesalpinia spinosa) and camu camu (Myrciaria dubia) to develop natural sunscreen and anti-aging products, the present study evaluated their antioxidant, anti-elastase, anti-collagenase and photoprotective activities in vitro. The hydroalcoholic extract of tara showed good antioxidant activity in different in vitro assays (DPPH, TEAC, hydroxyl radical, superoxide radical), and it also inhibits collagenase enzyme better than the positive control epigallocatechin gallate (EC50 = 162.78 and 321.41 µg/ml, respectively). The hydroalcoholic extract of camu camu, despite its high content of ascorbic acid, did not show a significant antioxidant activity, but instead, in a culture of 3T3 fibroblasts it exerted at good protective effect in vitro (43.6%) against UV-B radiation. It is recommended to study the association of both extracts as a basis for developing an anti-aging product or a sunscreen with a dual mechanism of action.
Palabras clave : antioxidant; camu camu; phenolic compounds; photoprotection; tara; UV-B.