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Revista de la Sociedad Química del Perú

Print version ISSN 1810-634X

Abstract

MORALES MOISELA, Marlon Miguel et al. Xantonas aisladas de Hypericum laricifolium y su actividad antiproliferativa contra las células HEP3B. Rev. Soc. Quím. Perú [online]. 2018, vol.84, n.4, pp.428-435. ISSN 1810-634X.

We describe here the isolation of 6 xanthones and one phenyl-γ-pyrone, together with 3-epibetulinic and quercetine from the aerial parts of Hypericum laricifolium Juss. (Hypericaceae), collected in Peru. Isolated compounds have been evaluated against proliferation of human hepatocellular carcinoma Hep3B cells. The most active compound was xanthone 3, with an inhibitory concentration (IC) of 12 µM. 50

Keywords : Xantonas; Hypericum laricifolium; células Hep3B; hepatocarcinoma.

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