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Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
Print version ISSN 2225-5109On-line version ISSN 2227-4731
Abstract
DIAZ-SIPION, Roberto; GUERRERO-MENDOZA, Mirko; CARRILO-LIZA, Romel and VENTURA-FLORES, Roberto. Detection of carbapenemase-producing Klebsiella pneumoniae in a hospital in northern Peru. Rev. Cuerpo Med. HNAAA [online]. 2020, vol.13, n.3, pp.303-306. Epub Sep 30, 2020. ISSN 2225-5109. http://dx.doi.org/10.35434/rcmhnaaa.2020.133.742.
Objective:
Communicate the first report of Klebsiella pneumoniae producing carbapenemases.
The study:
Microbiological diagnosis using phenotypic methods: double disc synergy, modified Hodge test, immunochromatography and carbapenemic inactivation.
Findings:
Four isolates (urine 3 and blood 1) of carbapenemase-producing K. pneumoniae were confirmed, which also presented a MIC of 4 and> = 8 for ertapenem and> = 16 µg / mL at imipenem and meropenem. Conclusion: Standardized phenotypic methods are useful in the confirmation of carbapenemases and with it an alternative for the best taking of therapeutic options and epidemiological surveillance.
Keywords : Carbapenem-Resistant Enterobacteriaceae; Clinical Laboratory Techniques; Klebsiella pneumoniae.