Abstract

MURGIA-FLORES, Amalia; ABAD-LICHAM, Milagros  and  DEZA-HUANES, Pedro. Short birth interval as a risk factor for ductal breast carcinoma in patients from northern Peru. Rev. Cuerpo Med. HNAAA [online]. 2021, vol.14, n.2, pp.119-123. ISSN 2225-5109.  http://dx.doi.org/10.35434/rcmhnaaa.2021.142.1020.

Background: Breast cancer is the most common histological type and it is a frequent cause of death in Peruvian women. Objective: To demonstrate that birth interval is a risk factor for ductal breast carcinoma. Material and Methods: This case-control study included 304 Peruvian women with histological diagnosis of breast carcinoma. They were divided into two groups, one with ductal carcinoma and another with non-ductal carcinoma (control). Besides birth interval; parity, age at first delivery, age at last delivery, age at histological diagnosis, interval from last delivery to diagnosis and molecular subtype were also evaluated. Results: The frequency of Ductal breast cancer was 78% in patients with short birth interval. The ratio between presence of short birth interval versus absence of short birth interval is 1.86 times higher in ductal breast cancer patients (CI 95%: 1,12-3,08). Additionally, there was significant association in age at first delivery ≤ 20 years (p<0,001) and interval from last delivery to diagnosis >10 years (p<0,001). Conclusion: short birth interval is a risk factor for ductal breast cancer, which can also be modified and used as a prevention element, so it should be included in the medical record.

Keywords : Breast cancer; carcinoma, ductal; birth intervals; parity.

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