SciELO - Scientific Electronic Library Online

vol.14 issue3Effects of a multimodal rehabilitation program in COVID-19 patients admitted to the Intensive Care Unit: a quasi-experimental studyMaternal factors associated with prematurity in pregnant women from a public hospital in Trujillo, Perú author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO


Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo

Print version ISSN 2225-5109On-line version ISSN 2227-4731


AMADO-TINEO, José et al. Factors associated with mortality in severe SARS-CoV-2 infection in a Peruvian hospital. Rev. Cuerpo Med. HNAAA [online]. 2021, vol.14, n.3, pp.280-286.  Epub Nov 26, 2021. ISSN 2225-5109.


To determine factors associated with mortality in patients with severe SARS-CoV-2 disease.

Materials and methods:

Retrospective study in patients older than 18 years hospitalized with severe disease (peripheral oxygen saturation <93% or radiological lung involvement > 30%) and a positive RT-PCR nasopharyngeal swab; in the Rebagliati hospital between March and May 2020. We reviewed electronic medical record, results of admission studies (laboratory and radiological) and treatment received. Bivariate and multivariate analysis were performed using cox regression.


337 patients were studied, 215 of them died (63.8%). 72.1% were male, mean age was 63.6 years (SD 15.3), time of disease evolution was 7.4 days, hospital stay 10.3 days, and 48.8% were on mechanical ventilation. Multivariate analysis found significance in age > 60 years (HR 1.76, IC95% 1.26-2.45), history of type 2 Diabetes (HR 1.63, IC95% 1.14-2.32), pulmonary involvement > 75% (HR 1.87, IC95% 1.37-2.56), leukocytes > 14000 x mm3 (HR 1.59, IC95% 1.15-2.20), serum albumin < 4.0 g/dL (HR 2.49, IC95% 1.30-4.75) and lactate > 1.5 mmol/L (HR: 1.766 IC95% 1.25-2.49).


Age older than 60 years, type 2 diabetes mellitus, severe pulmonary involvement, leukocytosis, low albumin, and high lactate at admission are factors associated with mortality in patients with severe SARS-CoV-2 disease.

Keywords : Risk Factors; Hospital Mortality; SARS-CoV-2; COVID-19; Coronavirus Infections.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )