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Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
versión impresa ISSN 2225-5109versión On-line ISSN 2227-4731
Resumen
PAZ-OLIVAS, Youmi et al. A dairy mixture fortified with iron and zinc improves hemoglobin levels in children aged 2 to 10 years in an andean community in Peru: randomized, double-blind controlled trial. Rev. Cuerpo Med. HNAAA [online]. 2021, vol.14, n.3, pp.304-310. Epub 26-Nov-2021. ISSN 2225-5109. http://dx.doi.org/10.35434/rcmhnaaa.2021.143.1250.
Objective:
Previous research agrees that food fortification is the best long-term strategy for preventing iron deficiency. Our goal is to evaluate the effect of a dairy mixture fortified with iron and zinc on hemoglobin levels in children aged 2 to 10 years.
Material and methods:
A randomized, double-blind, controlled clinical trial was conducted in a community located 2,590 meters above sea level. Children with normal levels of hemoglobin or mild anemia were included. We assign participants to receive the iron-zinc-fortified dairy mixture or an unfortified dairy mixture. The supplement was administered five days a week for 24 weeks. Our main result was the corrected hemoglobin level taking into account the height above sea level and anthropometric indices were evaluated as a secondary result. The magnitude of the difference observed between the groups was estimated by the Student t-test. All analyzes were done with the intention to treat.
Results:
67 children were randomly assigned, intervention: n=32 and control: n=35. The mean age was 5.8 years; 30 were women. Hemoglobin at the end of the follow-up was 13.1 g/dL (0.9) in the experimental group, while, in the control group, it was 12.1 g/dL (0.8); p <0.001. Likewise, a positive difference was evidenced in the anthropometric indicators in the experimental group.
Conclusion:
Dairy mixture fortified with iron and zinc increases hemoglobin levels and anthropometric indices in children from 2 to 10 years old.
Palabras clave : Child; Dairy mixture; Iron; Zinc; Hemoglobins; Peru.