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Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo

Print version ISSN 2225-5109On-line version ISSN 2227-4731

Abstract

SAAVEDRA-CAMACHO, Johnny Leandro et al. Use of radiological imaging and serology by Western Blot for the diagnosis of neurocysticercosis in a hospital in northern Peru. Rev. Cuerpo Med. HNAAA [online]. 2021, vol.14, n.3, pp.311-315.  Epub Nov 26, 2021. ISSN 2225-5109.  http://dx.doi.org/10.35434/rcmhnaaa.2021.143.1251.

Introduction:

Neurocysticercosis (NCC) is a parasitic zoonosis of the central nervous system caused by the tapeworm Taenia solium, which affects developing countries with poor basic sanitation.

Objective:

To describe the use and concordance of radiological tomography (CT) or magnetic resonance imaging (MRI) and western blot (WB) serology in the diagnosis of NCC in a hospital in northern Peru.

Material and Methods:

Retrospective observational study. The medical history was the unit of analysis. The cases were searched in the Epidemiology office using the ICD-10-B69 and registry of the Laboratory of Parasitology, Metaxenics and Zoonoses of the same hospital, in the period from 2015 to 2017.

Results:

67 medicales records were studied, which complied with the absolute diagnostic criteria for NCC. The patients were men in 55.2% and had a mean age of 40.2 (± 17.8) years. 35.9% had a positive result by WB (19/39), cystic lesions with scolex were observed in 25.4% of the CT and in 29.6 of the MRI. The concordance observed between the serological test with CT and MRI was poor, with (Kappa = 0.073, 95% CI: 0.053 - 1.084) and (Kappa = 0.112, 95% CI: 0.092 - 1.092) and a percentage of agreement of 42.0% and 45.7% respectively.

Conclusions:

Differentiated use and poor concordance between the WB serological test and radiological imaging are performed in patients with a diagnosis of neurocysticercosis in the studied population.

Keywords : Neurocysticercosis; Diagnostic Imaging; Serologic Tests; Diagnostic Techniques and Procedures.

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