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Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
Print version ISSN 2225-5109On-line version ISSN 2227-4731
Abstract
RODRIGUEZ-PORTILLA, Ricardo et al. Septic shock, hypercalcemia and hemophagocytic syndrome due to paracoccidioidomycosis in a 3-year-old girl. Rev. Cuerpo Med. HNAAA [online]. 2021, vol.14, n.3, pp.375-378. Epub Nov 26, 2021. ISSN 2225-5109. http://dx.doi.org/10.35434/rcmhnaaa.2021.143.1259.
Objetive:
Report the case of a girl who presented septic shock, hypercalcemia and hemophagocytic syndrome due to paracoccidioidomycosis.
Case report:
3-year-old female patient with 2-month illness characterized by fever, lymphadenopathy, weight loss, abdominal distention, and severe anemia. She arrived in poor general condition, developed septic shock and a hemophagocytic syndrome. The hypercalcemia and dermal lesions were striking. A cervical ganglion biopsy and bone marrow aspirate were performed. In the latter, images compatible with Paracoccidioides were found, which were then confirmed with Grocott's stain. She was treated with amphotericin B and trimethoprim-sulfamethoxazole. The evolution was favorable and serum calcium came back to normal ranges.
Conclusion:
Complications caused by paracoccidioidomycosis are rare; however, the epidemiological history and bone marrow aspirate should guide the diagnosis and allow prompt treatment.
Keywords : Paracoccidioidomycosis; Shock, Septic; Hypercalcemia; Lymphohistiocytosis, Hemophagocytic; Child, Preschool.