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Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo

Print version ISSN 2225-5109On-line version ISSN 2227-4731


RODRIGUEZ-PORTILLA, Ricardo et al. Septic shock, hypercalcemia and hemophagocytic syndrome due to paracoccidioidomycosis in a 3-year-old girl. Rev. Cuerpo Med. HNAAA [online]. 2021, vol.14, n.3, pp.375-378.  Epub Nov 26, 2021. ISSN 2225-5109.


Report the case of a girl who presented septic shock, hypercalcemia and hemophagocytic syndrome due to paracoccidioidomycosis.

Case report:

3-year-old female patient with 2-month illness characterized by fever, lymphadenopathy, weight loss, abdominal distention, and severe anemia. She arrived in poor general condition, developed septic shock and a hemophagocytic syndrome. The hypercalcemia and dermal lesions were striking. A cervical ganglion biopsy and bone marrow aspirate were performed. In the latter, images compatible with Paracoccidioides were found, which were then confirmed with Grocott's stain. She was treated with amphotericin B and trimethoprim-sulfamethoxazole. The evolution was favorable and serum calcium came back to normal ranges.


Complications caused by paracoccidioidomycosis are rare; however, the epidemiological history and bone marrow aspirate should guide the diagnosis and allow prompt treatment.

Keywords : Paracoccidioidomycosis; Shock, Septic; Hypercalcemia; Lymphohistiocytosis, Hemophagocytic; Child, Preschool.

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