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Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
Print version ISSN 2225-5109On-line version ISSN 2227-4731
Abstract
CONCEPCION-ZAVALETA, Marcio et al. Acromegaly due to pituitary macroadenoma in a patient with McCune-Albright syndrome. Case report and literature overview. Rev. Cuerpo Med. HNAAA [online]. 2022, vol.15, n.2, pp.273-276. Epub June 10, 2022. ISSN 2225-5109. http://dx.doi.org/10.35434/rcmhnaaa.2022.152.1136.
Background:
McCune-Albright syndrome (MAS) is a rare disease characterized by the triad: café-au-lait skin spots, polyostotic fibrous dysplasia, and precocious puberty. It can affect various hormonal axes, including growth hormone (GH), and may be associated with acromegaly.
Case report:
we describe the case of a 44-year-old woman with peripheral precocious puberty, abnormal uterine bleeding, growth of the hands and feet, prognathism, frontal prominence, café-au-lait spots, and stony tumors on the face and forearms.
Results:
supported by laboratory and imaging tests, the diagnoses of acromegaly, hypogonadotropic hypogonadism and McCune-Albright syndrome were reached. The patient underwent surgical treatment with persistence of clinical and laboratory disease.
Conclusion:
timely diagnosis and treatment of acromegaly and its complications will provide a better prognosis for patients with mas
Keywords : acromegaly; growth hormone-secreting pituitary adenoma; fibrous dysplasia, polyostotic.
