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Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
Print version ISSN 2225-5109On-line version ISSN 2227-4731
Abstract
VALDIVIA-TAPIA, María del Carmen; VARGAS-VEGA, Marilú Alicia; CARREAZO, NY and RAMIREZ-CORTEZ, Grimaldo de los A.. Severe rhabdomyolysis in an infant with multisystem inflammatory syndrome related to covid -19 (mis-c). Rev. Cuerpo Med. HNAAA [online]. 2022, vol.15, n.4, e1624. Epub Feb 28, 2023. ISSN 2225-5109. http://dx.doi.org/10.35434/rcmhnaaa.2022.154.1624.
Introduction:
A case of severe rhabdomyolysis associated with multisystem inflammatory syndrome related to COVID-19 (MIS-C).
Case of report:
is presented in a one-year 10-month-old boy who presented digestive symptoms, myalgia, weakness, fever, and dark urine. COVID-19 IgM (-) IgG (+) serological test, COVID-19 PCR negative. Initial creatine kinase (CK) presented non-dosable values, with the highest reported level being 517,600 U/L. The creatinine value remained normal throughout the hospitalization. He received human immunoglobulin 2 g/Kg, Methylprednisolone 10 mg/Kg/d, and acetylsalicylic acid to manage MIS-C. Aggressive hydration and urine alkalinization were provided to manage rhabdomyolysis.
Conclusion:
Positive evolution with discharge after ten days. Few reported cases of rhabdomyolysis are associated with MIS-C and none with such high CK values. Based on the possible complications, performing CK dosing in all patients with MIS-C is suggested routinely.
Keywords : Rhabdomyolysis; SARS-CoV-2; Multisystem Inflammatory Syndrome in Children (MIS-C); Renal Insufficiency.
