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Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
Print version ISSN 2225-5109On-line version ISSN 2227-4731
Abstract
ALVARADO-GAMARRA, Giancarlo et al. Clinical features and survival in pediatric oncohematological patients with COVID-19 in a referral Hospital of Peruvian Social Health Insurance, during 2020-2021. Rev. Cuerpo Med. HNAAA [online]. 2023, vol.16, n.1, pp.51-57. Epub Mar 27, 2023. ISSN 2225-5109. http://dx.doi.org/10.35434/rcmhnaaa.2023.161.1702.
Introduction:
In Latin America, there are few studies and heterogeneous results on pediatric oncohematology patients with COVID-19. Objective: To describe the clinical characteristics and survival of pediatric oncohematology patients with COVID-19 in a hospital in Lima-Peru, 2020-2021.
Methods:
Retrospective longitudinal study of hospitalized patients under 14 years of age. The data was collected from the medical records.
Results:
We included 30 patients, mostly men and schoolchildren, predominantly fever, respiratory and gastrointestinal symptoms, hematological neoplasia, and advanced oncological disease. The majority developed mild-moderate disease, but they also presented severe evolution requiring critical areas, with high mortality in hospitalization (13.3%) and low survival during follow-up (at 526 days, 59.26%, 95% CI 36 .53 to 76.20%). Survival increased with the start of chemotherapy, and decreased in patients in palliative condition, with respiratory support and shock.
Conclusion:
Most developed mild-moderate disease. However, SARS-CoV-2 can also cause severe involvement, death, and poor survival in oncohematological patients.
Keywords : COVID-19; Neoplasms; leukemia; Child; Pediatrics, Peru.