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Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
Print version ISSN 2225-5109On-line version ISSN 2227-4731
Abstract
FARFAN-CHAVEZ, Gabriel Luis and PEREZ-ACUNA MEDINA, Alexandra Katherine. Modified antituberculosis regimen due to hepatotoxicity caused by Pyrazinamide: Case report. Rev. Cuerpo Med. HNAAA [online]. 2023, vol.16, n.1, pp.134-137. Epub Mar 27, 2023. ISSN 2225-5109. http://dx.doi.org/10.35434/rcmhnaaa.2023.161.1645.
Introduction:
Tuberculosis is one of the 10 leading causes of death worldwide. In 2020, it caused 1.5 million deaths. It is estimated that it reached 10.0 million new cases during the same year.
Case of report:
93-year-old male, history of pulmonary TB 15 years ago and current TB contact. He presented dyspnea and pleuritic pain for 4 months. Thoracocentesis concludes exudate, pleural biopsy compatible with non-caseating granulomatous pleurisy. Receive antituberculosis regimen, developing hepatic RAFA. Pharmacological challenge is performed to design a new treatment scheme. Patient manages to recover. It is concluded that the management of tuberculosis should be individualized.
Keywords : pleural tuberculosis; pleural effusion; adverse effects; antitubercular drugs.
