Abstract

CANUL-CANCHE, Jaqueline; SUAREZ-GUERRERO, Nicolás Gustavo; SUAREZ-PUERTO, Nicolás Gustavo  and  GONZALEZ-LOSA, María del Refugio. Effectiveness of loop electrosurgical excision of cervical lesions caused by human papillomavirus. Rev Per Ginecol obstet. [online]. 2013, vol.59, n.2, pp.115-118. ISSN 2304-5132.

Background: Human papillomavirus infection causes cervical cancer and precursor lesions. Treatment effectiveness is determined by histopathology. Persistence of the virus may condition the appearance of new lesions. Objectives: To determine effectiveness of loop electrosurgical excision procedure for HPV clearance in patients with cervical intraepithelial neoplasia. Design: Prospective, descriptive, longitudinal, observational study. setting: Hospital General de la Secretaria de Salud (SS) en Chetumal, Quintana Roo, Mexico. Participants: Women with clinical dysplasia and cytology diagnosis of LGSIL or HGSIL. Interventions: One hundred four women referred to the colposcopy clinic were enrolled; a cervical sample was taken to identify HPV. All were treated by loop diathermy. HPV positive patients were tested again 8 weeks later for new HPV determination. Main outcome measures: Negativization of papillomavirus. Results: In the first sample 26.9% were virus positive. Histopathology diagnosis was respectively low grade (35.7%) and high grade (64.3%) squamous intraepithelial lesion. None of the 28 patients showed viral DNA 8 weeks later. Conclusions: Treatment by loop electrosurgical excision was effective to eliminate viral DNA.

Keywords : Loop electrosurgical excision procedure; human papillomavirus; effectiveness; Mexico.

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