SciELO - Scientific Electronic Library Online

vol.59 issue3Twin reverse arterial perfusion (TRAP) sequence in monochorionic twin pregnancy with acardiac fetus author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO


Revista Peruana de Ginecología y Obstetricia

On-line version ISSN 2304-5132


POMA, Pedro A.. Pregnancy cholestasis. Rev. peru. ginecol. obstet. [online]. 2013, vol.59, n.3, pp.207-224. ISSN 2304-5132.

Intrahepatic cholestasis of pregnancy (ICP) consists in pruritus that develops in the second half of pregnancy and is not associated with other dermatological or systemic problems. ICP diagnosis is confirmed by increase in maternal serum bilirubin, liver enzymes and fasting biliary acids. ICP is associated with fetal meconium passage, prematurity and fetal death. Treatment with ursodeoxycholic acid (UDCA) improves pruritus, maternal laboratory anomalies and fetal outcomes. ICP has a relative benign maternal course but compared to women without this complication ICP women have increased risk in developing hepatobiliar problems, breast cancer and hypothyroidism. Long-term follow up is recommended.

Keywords : Pregnancy; pruritus; cholestasis; adverse fetal out-comes.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )