Abstract

GOMEZ CARBAJAL, Luis Martín. Pathophysiology of preeclampsia. Rev. peru. ginecol. obstet. [online]. 2014, vol.60, n.4, pp.321-332. ISSN 2304-5132.

Preeclampsia is one of the most frequent and serious disorders of pregnancy. It is a significant contributor of maternal and perinatal mortality worldwide. An important amount of research has been devoted in the research of preeclampsia in the recent years; nonetheless, its pathophysiology is yet to be completely understood. In this review, we will discuss new proposed theories on the pathophysiology of preeclampsia. Genetic and angiogenic aspects of preeclampsia will be reviewed elsewhere in this issue.

Keywords : placental ischemia; endothelial dysfunction; nitric oxide; oxidative stress; endoplasmic reticulum stress; Chlamydia pneumoniae; fetuin-A.

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