Abstract

LOPEZ-SANCHEZ, Geraldine; REYNA-VILLASMIL, Eduardo  and  TORRES-CEPEDA, Duly. Acute fatty liver of pregnancy. Case report. Rev. peru. ginecol. obstet. [online]. 2018, vol.64, n.4, pp.667-670. ISSN 2304-5132.  http://dx.doi.org/10.31403/rpgo.v64i2137.

Acute fatty liver of pregnancy is a rare condition that occurs most frequently in the third trimester. There is severe liver dysfunction, associated with renal impairment and prolonged clotting time. These hepatic and extra-hepatic complications can cause significant maternal morbidity and mortality, and the definitive treatment is the immediate interruption of pregnancy. We present a case of complicated acute fatty liver of pregnancy in a primigravid, 40-year-old patient who presented epigastralgia of sudden onset together with generalized lethargy, nausea and vomiting. Laboratory exams showed impaired hepatic and renal function along with hypoglycemia; we diagnosed acute fatty liver of pregnancy. The patient was treated to correct the metabolic alterations, and cesarean section was performed with improvement of laboratory parameters and complete postoperative recovery.

Keywords : Acute fatty liver of pregnancy; Liver; Pregnancy; Liver injury.

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