Abstract

VALLADARES GUTIERREZ, Elías Alexis. Risks factors for maternal near miss due to spontaneous hepatic rupture in severe preeclampsia. Rev. peru. ginecol. obstet. [online]. 2019, vol.65, n.4, pp.443-448. ISSN 2304-5132.  http://dx.doi.org/10.31403/rpgo.v65i2202.

Introduction: Spontaneous hepatic rupture is one of the most feared complications of pregnancy that leads to maternal near miss and death and is mainly associated with severe preeclampsia. Objective: To determine risk factors for spontaneous hepatic rupture in pregnant women with severe preeclampsia. Methods: We performed a cross-sectional, retrospective case-control study during the period January 1, 2006 through December 31, 2018. Thirty-one women with severe preeclampsia who presented hepatic rupture (cases) were compared to sixty-two controls (women with severe preeclampsia without hepatic rupture), in a ratio of two controls per case. Results: Factors significantly associated with hepatic rupture in women with severe preeclampsia were HELLP syndrome (OR = 3.42, 95% CI: 1.51 to 6.17), advanced maternal age (OR = 2.18; 95% CI: 1.13 to 5.02) and eclampsia (OR = 1.94, 95% CI: 1.09 to 4.38). Conclusions: In this study of pregnant women with severe preeclampsia, advanced maternal age was a risk factor for spontaneous hepatic rupture, and HELLP syndrome and eclampsia were associated factors.

Keywords : Pregnancy complication; Preeclampsia.

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