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Revista Peruana de Ginecología y Obstetricia
On-line version ISSN 2304-5132
Abstract
TORRES-CEPEDA, Duly; RONDON-TAPIA, Martha and REYNA-VILLASMIL, Eduardo. Extrapulmonary small cell carcinoma of the breast. Case report. Rev. peru. ginecol. obstet. [online]. 2022, vol.68, n.1, 00016. Epub Feb 24, 2022. ISSN 2304-5132. http://dx.doi.org/10.31403/rpgo.v68i2393.
Small cell carcinoma accounts for 20% of lung cancers; it rarely occurs at other sites. Extrapulmonary small cell carcinoma is aggressive, with a propensity for regional and distant spread. This type of carcinoma is a rare breast neoplasm. Although the clinical appearance is nonspecific, it often responds well to therapy and has a good prognosis of survival. We present the case of a 50-year-old woman with extrapulmonary small cell carcinoma of the breast. Physical examination showed a 4 x 3 x 3 centimeters lesion confirmed by magnetic resonance imaging of the left breast. The diagnosis was made by biopsy showing characteristic small, round, lymphocyte-like cells with hyperchromatic nuclei and scant cytoplasm, compatible with small cell carcinoma of the breast. The patient was treated with chemotherapy before undergoing total mastectomy and lymph node resection.
Keywords : Breast; Breast neoplasms, extrapulmonary small cell carcinoma.