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Revista Peruana de Ginecología y Obstetricia

versión On-line ISSN 2304-5132

Resumen

TORRES-CEPEDA, Duly; RONDON-TAPIA, Martha  y  REYNA-VILLASMIL, Eduardo. Primary primitive neuroectodermal tumor of the ovary. Rev. peru. ginecol. obstet. [online]. 2022, vol.68, n.2, 00015.  Epub 06-Jul-2022. ISSN 2304-5132.  http://dx.doi.org/10.31403/rpgo.v68i2421.

Primitive neuroectodermal tumor of the ovary is a rare and aggressive small round cell soft tissue sarcoma of neural origin that is usually associated with high morbidity and mortality. Immunohistochemistry is a useful adjunct in the differential diagnosis. We describe a case of a primitive neuroectodermal tumor of the ovary in a 21-yearold nulliparous patient who reported pain and increased abdominal circumference. Ultrasonography showed a solid-cystic heterogeneous tumor apparently originating from the left adnexa. Magnetic resonance imaging confirmed the presence of a tumor extending into the left iliac fossa without local organ involvement or regional or distant metastases. Tumor markers were all within the normal range. During laparotomy, a left ovarian tumor was observed with a normal right ovary. Left salpingo-oophorectomy was performed due the size of the tumor, right ovarian wedge resection, pelvic lymphadenectomy and omentectomy. Histopathologic examination revealed tumor composed of sheets of round cells. The tumor cells were positive for chromogranin A, synaptophysin, vimentin and neuron-specific enolase, which confirmed the diagnosis of a primitive neuroendocrine tumor of the left ovary originating from immature cystic teratoma. The patient refused postoperative chemotherapy.

Palabras clave : Ovary primitive neuroectodermal tumor, Soft tissue neoplasm, Sarcoma; Immunohistochemistry..

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