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Revista Peruana de Ginecología y Obstetricia

On-line version ISSN 2304-5132


TORRES-CEPEDA, Duly; RONDON-TAPIA, Martha  and  REYNA-VILLASMIL, Eduardo. Primary vulvar Merkel cell carcinoma. Rev. peru. ginecol. obstet. [online]. 2022, vol.68, n.3, 00018.  Epub Sep 22, 2022. ISSN 2304-5132.

Merkel cells were originally described in the stratum basale of the epidermis with neuroendocrine properties. Merkel cell carcinoma of the vulva is an extremely rare and highly aggressive neoplasm. There are few cases of these tumors, most of which have been considered neuroendocrine tumors. The histologic origin and etiology of this disease are controversial. It is known for his aggressive behavior and propensity for early diffusion. Because of its rarity in this location, it is unclear whether it behaves differently from similar skin carcinomas in other locations. A case of primary vulvar Merkel cell carcinoma is presented. Excisional biopsy examination revealed a 4 x 3-centimeter tumor in the posterior third of the left labium majus of the vulva without lymph node involvement. The patient underwent radical vulvectomy and bilateral inguinal lymph node dissection. Postoperative histological evaluation showed no regional or distant metastases.

Keywords : Vulva; Carcinoma; Merkel cell; Vulvar neoplasms.

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