Abstract

REYNA-VILLASMIL, Eduardo; RONDON-TAPIA, Martha  and  TORRES-CEPEDA, Duly. Low-grade endometrial stromal sarcoma. Rev. peru. ginecol. obstet. [online]. 2022, vol.68, n.4, 00011.  Epub Nov 30, 2022. ISSN 2304-5132.  http://dx.doi.org/10.31403/rpgo.v68i2461.

Endometrial stromal sarcoma is a rare malignant neoplasm that originates in the endometrial stroma. It can have several forms of differentiation, including smooth muscle and sex cord. Low-grade endometrial stromal sarcoma is a rare type of endometrial tumor, constituting only 0.2% of all uterine neoplasms. Its etiology is unknown, but some cases are associated with obesity, polycystic ovary syndrome, diabetes mellitus, early menarche, and estrogen replacement therapy or tamoxifen. Symptomatology is nonspecific, ranging from pelvic pain to progressive abnormal genital bleeding, and is difficult to recognize by radiological imaging. In most cases, the diagnosis is made by pathological evaluation. Immunohistochemical staining can also help differentiate it from other neoplasms. Therefore, it is important to have a high index of suspicion for this type of rare neoplasm. Its treatment is surgical and its follow-up should be long term, due to the high risk of late recurrences and metastasis. A case of low-grade endometrial stromal sarcoma is presented.

Keywords : Endometrial stromal sarcoma; low grade; Uterine neoplasms.

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