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Revista de la Facultad de Medicina Humana
versión impresa ISSN 1814-5469versión On-line ISSN 2308-0531
Resumen
ARTEAGA-HUANCA, Víctor; LOO, María; LOO, Haylin y CEDILLO-RAMIREZ, Lucy. Association between characteristics of mammographic calcifications and maligine neoplasia in a national hospital, 2017. Rev. Fac. Med. Hum. [online]. 2020, vol.20, n.1, pp.70-75. ISSN 1814-5469. http://dx.doi.org/10.25176/rfmh.v20i1.2548.
Introduction:
The presence of calcifications may be useful for the diagnosis of breast neoplasia.
Objective:
To determine the association between the characteristics of mammographic calcifications and malignant neoplasia.
Methods:
Observational, analytical, retrospective of cases and controls. Developed in the Gynecology Breast Pathology Unit. Female patients with mammogram suggestive of malignant neoplasm with a positive malignancy biopsy were included as cases, and 67 patients without histological evidence of malignancy as controls.
Results:
The average age of the cases was 54.12 years, in the controls 50.34. 50.9% (59) are older than or equal to 50 years, OR 2,399 95% CI (1,125-5,114) p = 0.022, of these 52.5% (31) had breast cancer. 9.5% (11) had calcifications suspicious of malignancy, the most frequent, the amorphous and the pleomorphic fine. 37.1% (43) of the total cases have the BI-RADS 0 category, 6.9% (8) BI-RADS 1, 8.6% (10) BI-RADS 2, 7.8 % (9) BI-RADS 3, 28.4% (33) BI-RADS 4, 8.6% (10) BI-RADS 5 and 2.6% (3) BI-RADS 6. 72, 7% (8) of patients with calcifications suspected of malignancy presented breast cancer. In the bivariate analysis, an OR of 4,163 was obtained. 95% CI (1,043-16,606) p = 0,031. In the multivariate analysis the association remained unchanged regardless of age and BI-RADS.
Conclusions:
Age 50 years or older and mammographic calcifications suspected of malignancy are associated factors for breast cancer.
Palabras clave : Breast cancer; Mammography; Malignant neoplasm (source: MeSH NLM)..