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Revista de la Facultad de Medicina Humana

Print version ISSN 1814-5469On-line version ISSN 2308-0531


VALDIVIA-GOMEZ, Anghella et al. Predictor factors for multidrug-resistant tuberculosis among patients with pulmonary tuberculosis in Huánuco, Peru. 2010-2015. Rev. Fac. Med. Hum. [online]. 2020, vol.20, n.2, pp.193-200. ISSN 1814-5469.


In the city of Huánuco and around the world, there is a progressive increase in cases of Tuberculosis and multidrug-resistant Tuberculosis, for this reason it was necessary to identify predictors to develop multidrug-resistant Tuberculosis.


To determine if persistent fever, cavitary radiographic pattern and positive smear microscopy at the first month of treatment, are predictors of multidrug-resistant Tuberculosis in patients with Pulmonary Tuberculosis, in four health facilities in the city of Huánuco, between January 2010 and December 2015.


Case and control study. We considered 37 cases and 111 controls. Data were collected from medical records.


The predictive factors found in the bivariate analysis were persistence of fever at 2 weeks (p = 0.001, OR 0.05, CI 0.01-0.5), cavitary radiographic pattern (p = 0.000, OR 11.6, 95%IC 4.6-26.5), and smear microscopy positivity at the first month of treatment (p = 0.00, OR 13.5, 95%CI 4.1-44.6). These were confirmed by multivariate analysis (p = 0.012, p = 0.00, p = 0.00 respectively).


The persistence of fever at two weeks, cavitary radiographic pattern and positive smear microscopy at the first month of treatment were predictive factors associated independently for the diagnosis of multidrug-resistant Tuberculosis.

Keywords : Drug-Resistant Tuberculosis; Case Studies; and Controls (source: MeSH NLM)..

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