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Revista de la Facultad de Medicina Humana
Print version ISSN 1814-5469On-line version ISSN 2308-0531
Abstract
VELARDE, Edwin Castillo; PACORA, Gloria Montero and LLAJARUNA, Sandra García. Association between hypoalbuminemia and hypophosphatemia with malnutrition in patients with chronic renal disease undergoing hemodialysis. Rev. Fac. Med. Hum. [online]. 2020, vol.20, n.3, pp.381-387. ISSN 1814-5469. http://dx.doi.org/10.25176/rfmh.v20i3.2968.
Introduction:
Malnutrition in hemodialysis patients is a consequence of various deficiency and hypercatabolic factors and constitutes a risk factor for morbidity and mortality.
Objective:
Determine the association between hypoalbuminemia and hypophosphatemia with the Subjective global assessment (SGA) C in patients with chronic renal disease on hemodialysis.
Methods:
Analytical cross-sectional study. Patients from the hemodialysis service of the Hospital Guillermo Almenara were studied. The Kruskal-Wallis test and multiple comparisons test were used for the association between continuous variables of malnutrition and the types of SGA. The square-chi test was used for the categorical variables hypoalbuminemia (≤3.5 g/dL) and hypophosphatemia (<3 mg/dL). The association with SGA C was analyzed.
Results:
131 patients were included and the median age was 63 years. 34% had hypoalbuminemia, 27% had hypophosphatemia and 14% had SGA C. 52% (68) of the patients presented alteration of at least one analyzed biomarker. Differences were found between SGA and albumin (p<0.001) and phosphorus (p=0.040). Patients with SGA C had a mean albumin of 3.1±0.74 and phosphorus of 2.88±1.54 and had a significant difference compared to those with SGA A (p<0.001 and P = 0.011, respectively). Chi-square analysis also demonstrated a significant association between SGA and hypoalbuminemia (p = 0.017) and hypophosphatemia (p=0.050).
Conclusion:
There is an association between SGA C and hypoalbuminemia and hypophosphatemia in patients with chronic kidney disease undergoing hemodialysis.
Keywords : Hypoalbuminemia; Hypophosphatemia; Malnutrition; Dialysis. (Source: MeSH NLM).