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Revista de la Facultad de Medicina Humana

Print version ISSN 1814-5469On-line version ISSN 2308-0531

Abstract

LAZARO, Alex Brandon López; MURILLO, Graciela Marilyn Aguilar; NECIOSUP, Alicia Pamela Muñoz  and  RIOS, Evelyn Goicochea. Hypoalbuminemia and mortality of sepsis from covid-19 in a Hospital in Chocope, Perú,2020. Rev. Fac. Med. Hum. [online]. 2021, vol.21, n.1, pp.12-18. ISSN 1814-5469.  http://dx.doi.org/10.25176/rfmh.v21i1.3437.

Introduction:

A correlational type investigation was carried out evaluating 145 patients with COVID-19 sepsis.

Objectives:

To determine whether hypoalbuminemia is a predictor of mortality and to identify the serum albumin value most frequently related to lethality.

Method:

Patients older than or equal to 18 years seen at Hospital II Chocope during May to August 2020 were included. Patients with oncological pathologies and incomplete medical records were excluded. The documentary analysis technique was used, by reviewing medical records.

Results:

There was a statistically significant association between hypoalbuminemia and mortality (p=0.014), patients with hypoalbuminemia had 3 times the risk of dying. (OR=3.97 95% CI of 1,24-12,74). Likewise, the highest sensitivity and specificity of the test was when the cut-off point for hypoalbuminemia was 1.38 g / dl. Finally, the most frequent comorbidity was arterial hypertension.

Conclusions:

Hypoalbuminemia can be a predictor of mortality in patients with sepsis due to COVID-19 at the Hospital de Chocope because it has a statistically significant association, with three times the risk of death. The highest sensitivity and specificity was obtained with an albuminemia cutoff of 1.38 g / dL. The most frequent comorbidity in patients with sepsis due to COVID-19 who died was arterial hypertension.

Keywords : Hypoalbuminemia; Mortality; Sepsis; COVID-19. (Source: MeSH NLM).

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