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Revista de la Facultad de Medicina Humana
Print version ISSN 1814-5469On-line version ISSN 2308-0531
Abstract
LAZO, Aníbal Díaz; BARRIENTOS HUAMANI, Carlos and CORDOVA ROSALES, Carlo. Factors associated with left ventricular hypertrophy in adults living at a high altitude city in Peru. Rev. Fac. Med. Hum. [online]. 2021, vol.21, n.1, pp.82-89. ISSN 1814-5469. http://dx.doi.org/10.25176/rfmh.v21i1.3270.
Introduction:
Left ventricular hypertrophy has been described in people who live at high altitudes.
Objective:
To determine the factors related to left ventricular hypertrophy (LVH) in adults.
Methods:
An observational, cross-sectional and analytical study was carried out in the Echocardiography Laboratory of the Hospital Regional Docente Clínico (HRDCQ) Daniel Alcides Carrión (HRDCQ) of Huancayo, Peru at 3,259 m.a.s.l. The sample was determined with a formula and the sampling was simple random. The inclusion criteria were: be 18 years of age or older; have an echocardiography study with a diagnosis of LVH. The exclusion criteria were: having valvular disease, congenital heart disease, dilated cardiomyopathy, acute cardiovascular event, and cardiac arrhythmia. The data were collected in a file. For the statistical analysis, the X2 test, student's t test, binary and multivariate logistic regression, odds ratio, 95% confidence interval were applied. P <0.050 was considered significant.
Results:
488 patients were included, the average age was 64 years (range: 18-98). In 58.9% (370) they were women. The factors related to LVH were arterial hypertension (OR=5 .31; 95% CI=3 .27 - 8.61), age older than 60 years (OR=2 .94; 95% CI=1 .93 - 4, 50), diabetes mellitus (OR=3 .33; 95% CI=1 .15 - 9.79), and obesity (OR=2 .21; 95% CI=1 .16 - 4.19) compared to patients without LVH. In patients with LVH, a higher left atrial volume index and left ventricular diastolic dysfunction were found.
Conclusions:
The factors related to LVH in adults were arterial hypertension, advanced age, diabetes mellitus and obesity.
Keywords : hypertensión obesity; diabetes mellitus; risk factors (Source: MeSH NLM)..