Abstract

VARGAS-PACHECO, Amelia  and  CORREA-LOPEZ, Lucy E.. Exercise as a protagonist in muscle plasticity and in the muscle as an endocrine organ: Implications in chronic diseases. Rev. Fac. Med. Hum. [online]. 2022, vol.22, n.1, pp.181-192.  Epub Dec 31, 2021. ISSN 1814-5469.  http://dx.doi.org/10.25176/rfmh.v22i1.4129.

The active skeletal muscle and the maintenance of muscle mass are essential for good health, wellness and disease prevention and treatment. It has recently been documented that the muscle, as an endocrine organ, is capable of synthesizing myokines. These peptides are secreted in response to muscular contractions induced by exercise, and can develop molecular communication with other tissues, improving cardiovascular, metabolic, and mental health. The endocrine function of a muscle continues to be in a constant investigation; however, knowledge up to date urges us to continue promoting physical activity. Additionally, the extended knowledge of myokines is useful to prescribe individualized physical exercise programs to each patient.

Keywords : Adaptive plasticity; muscles; cytokines; physical exercise; motor activity; chronic disease (Source : MeSH - NLM)..

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