Introduction:

Anaplastic Large T-Cell Lymphoma is an infrequent pathology, determined by the expression of CD30, with different characteristics in its presentation and being more aggressive according to ALK expression.

Objectives:

The present study seeks to determine the epidemiological, clinicopathological, and prognostic characteristics of patients with Anaplastic Large T-Cell Lymphoma.

Methods:

Descriptive, retrospective study of patients diagnosed with Anaplastic Large T-Cell Lymphoma of the National Institute of Neoplastic Diseases (INEN) between 2006 and 2016.

Results:

The pathology of 86 patients was analyzed and reviewed, 57% were men and 33 % women; of the total population, 21.9% were positive for ALK, 48 of the patients were found in CD I and II, and 36 between stages III and IV. 57 patients had low or low-intermediate risk, while 26 had high-intermediate and high risk. The estimated overall survival was 40.8% at 5 years; in the group of patients with ALK + it was 67.4%, and in the group with ALK-, it was estimated at 30.2%.

Conclusions:

Anaplastic Large T-Cell Lymphoma is an aggressive disease with a heterogeneous distribution to age and slightly more frequent in males, with ALK and the international prognostic index as important prognostic factors.

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