Abstract

CASTRO-MUJICA, María del Carmen. Clinical implications of the molecular biology of prostate cancer: Review Article. Rev. Fac. Med. Hum. [online]. 2022, vol.22, n.3, pp.597-613.  Epub July 09, 2022. ISSN 1814-5469.  http://dx.doi.org/10.25176/rfmh.v22i3.5043.

To understand the term genomic heterogeneity in prostate cancer, we must understand the clonal genomic evolution of cancer, as well as know that it is a dynamic and evolutionary phenomenon. Knowing the genome of prostate cancer not only allows us to have a vision over time of the genomic alterations, that occur during its different stages, but also to learn about the mechanisms of metastasis. In addition, knowing the hereditary component of prostate cancer allows us to evaluate patients and be able to identify if we are dealing with a family at risk.

Keywords : Prostate Neoplasms; Genetic Heterogeneity; Germ Line Mutation. (Source: MeSH NLM)..

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