Introduction:

Superior vena cava syndrome is a rare entity in literature.

Clinical Case:

We present the case of a 32-year-old male patient who visited the Emergency Department due to sudden facial cyanosis, facial pressure, dry cough, odynophagia, and dysphonia, without reporting dyspnea. On physical examination: face, neck, and supraclavicular region edema, central cyanosis, petechiae, and subungual haemorrhage in the hands. History of colon neoplasia, with colostomy and placement of a left subclavian Port catheter 2 years ago. CT angiography shows a filling defect due to recent thrombosis in the internal jugular veins, left and right brachiocephalic veins, arch of the azygos, and superior vena cava in all its lumen. Neoplastic pathology associated with invasive procedures with central venous catheters increases the risk of presentation, as in our case, with severe intrinsic complete venous obstruction. Surgical treatment with thrombectomy by mechanical aspiration allowed total resection of the thrombus and full restoration of circulation.

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