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Revista de la Facultad de Medicina Humana
Print version ISSN 1814-5469On-line version ISSN 2308-0531
Abstract
SCARSI-MEJIA, Ottavia and GARCIA-MORENO, Katerine Maite. SOFA and qSOFA scales as mortality prognosis in patients diagnosed with sepsis in a Peruvian Clinic. Rev. Fac. Med. Hum. [online]. 2022, vol.22, n.4, pp.804-812. Epub Oct 12, 2022. ISSN 1814-5469. http://dx.doi.org/10.25176/rfmh.v22i4.5066.
Introduction:
Sepsis is a clinical condition that seriously threatens the balance of the organism and is still a leading cause of mortality. Therefore, clinical management aims at timely classification and implementation of emergency measures based on scale systems for detection that help reduce patient complications. Hence the importance of using SOFA (Sequential Organ Failure Assessment), qSOFA (quick SOFA) in the different services in hospitalized patients.
Objectives:
To evaluate the usefulness of the SOFA and qSOFA scales as a prognosis of mortality in patients with sepsis hospitalized in the intensive care unit (ICU) of the Good Hope Clinic from January to December 2015.
Methods:
Retrospective study of adult patients hospitalized in service ICU/NICU with sepsis diagnoses. The epidemiological, clinical, and laboratory data necessary to apply the SOFA and qSOFA scales were collected. A description of the variables studied, an analysis, and the scoring systems compared in the ROC curve were made.
Results:
The main infectious focus was respiratory (41.5%). 28.3% of the patients died. The variables creatinine and serum lactate proved to be statistically significant with OR=11.67 (95% CI 2.58-52.85, p<0.001) and OR=5.78 (95% CI 1.45-23.03, p=0.009), respectively. The SOFA AUC was 0.698, p=0.026, 95% CI (0.54-0.85), proving to be statistically significant. A cut-off point of 7.5 with a sensitivity of 46.7% and 86.8% specificity was found. The QSOFA scale did not show a statistically significant association.
Conclusions:
The SOFA scale was associated with the probability of death in patients with sepsis admitted to the ICU/NICU service.
Keywords : Critical care; Mortality; SOFA; qSOFA. (Source: MeSH NLM)..