Abstract

GARCIA-GALICIA, Arturo et al. Identification of human Papillomavirus Genotypes in juvenile Laryngeal Papillomatosis. Three-year experience in a concentration hospital in Puebla, Mexico. Rev. Fac. Med. Hum. [online]. 2023, vol.23, n.1, pp.87-92.  Epub Jan 25, 2023. ISSN 1814-5469.  http://dx.doi.org/10.25176/rfmh.v23i1.5088.

Juvenile laryngeal papillomatosis (JLP) is a chronic benign disease of viral etiology with an aggressive clinical course. In Mexico, the genotypes of the Human Papilloma Virus (HPV) that cause the disease have been poorly studied. This study aimed to identify HPV genotypes in PLJ patients. A descriptive and retrospective study was carried out, and the records of patients with PLJ treated in Mexico were reviewed in 2018-2021. HPV was identified in all patients for genomes 6, 11, 16, and 18. 9 patients were included, 56% women, mean age of 9.5 ± 5.7 years; 7 patients registered positivity for HPV-11 and 2 for HPV-6. The average age at diagnosis was 2.35 ± 1.77 years, with an average of 12 ± 11.56 surgical procedures. In conclusion, the most frequent genotypes in patients with PLJ were HPV-6 and HPV-11, with the latter predominating.

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