Introduction:

PNETs are neoplasms derived from the neural crest. They are classified into: 1) central PNET, 2) neuroblastoma and 3) peripheral PNET. The objective is to report the case of a 32-year-old female patient with an inguinal tumor with immunohistochemical profile compatible for PNET treated with chemotherapy and induction thalidomide.

Clinical case:

32-year-old female patient presented with a tumor in the inguinal region, the biopsy indicated: round cell neoplasm with small, hyperchromatic and monomorphic nuclei; the immunohistochemical profile was synaptophysin positive, neurofilament positive, SOX-11 positive and Ki-67: 70%, induction chemotherapy was started with carboplatin- etoposide and thalidomide achieving a 60% reduction in tumor size, followed by compartmentectomy with regional lymphadenectomy and later adjuvant radiotherapy and maintenance chemotherapy.

Conclusions:

In this patient, multidisciplinary treatment for pPNET benefited from the use of chemotherapy and thalidomide in the induction phase.

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