Abstract

QUINONES CERNA, Claudio et al. Effect of flavonoids extracted from Equisetum bogotense (Equisetaceae) on the levels of TNF-α in experimentally induced inflammation in Mus musculus BALB / c. Arnaldoa [online]. 2019, vol.26, n.3, pp.1075-1082. ISSN 1815-8242.  http://dx.doi.org/10.22497/arnaldoa.263.26314.

Equisetum arvense (Equisetaceae) is a plant that has anti-inflammatory effects due to its phytochemical compounds such as flavonoids, which act at the level of proinflammatory cytokines, mainly TNF-α. However, other species of Equisetum are known in Peru, of which these effects have not been demonstrated. One of these species is Equisetum bogotense, from which the flavonoids were extracted and inoculated in Mus musculus BALB / c. These flavonoids acted on the levels of TNF-α produced in the inflammation experimentally induced in Mus musculus BALB / c by the inoculation of carrageenans. For the quantification of TNF-α levels the ELISA test was performed, obtaining that the flavonoids reduced the levels of TNF-α, however there was no significant difference between the concentrations used.

Keywords : Equisetum bogotense; TNF; inflammation; Mus musculus; elisa; flavonoids.

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