Aim

: To determine the in vitro antimicrobial activity of the hydroalcoholic extracts of aguaymanto fruits (Physalis peruviana L.) and eucalyptus leaves (Eucalyptus globulus Labill.) in concentrations of 40%, 70% and 100% against Staphylococcus aureus.

Material and methods

: It was a comparative and experimental study; an oxacillin resistant strain of Staphylococcus aureus was analyzed with which 15 repetitions were performed for each concentration plus a positive control with vancomycin. The disk-diffusion antibiogram test was used to assess antimicrobial activity. The obtained data were processed in the SPSS Statistics 22 program and were statistically analyzed according to the ANOVA test and the Duncan test.

Results

: There was a significant difference (p <0.001) in the results of the 3 concentrations of the hydroalcoholic extract of Physalis peruviana L. with the vancomycin control; due to these did not present an antimicrobial activity comparable to the control. As for the hydroalcoholic extract of Eucalyptus globulus Labill., according to Duncan’s test, its antimicrobial activity at a concentration of 100% (16.00 mm) was very similar to the effect produced by vancomycin (16.30 mm) against Staphylococcus aureus.

Conclusion

: The hydroalcoholic extract of eucalyptus in the 100% concentration was the one with the highest antimicrobial activity against S. aureus.

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