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Arnaldoa
Print version ISSN 1815-8242On-line version ISSN 2413-3299
Abstract
HUAMAN, Juan J. Pedro; ZAVALETA ESPEJO, Gina G. and BEJARANO NAVARRETE, Estefany M.. Antibacterial applications of silver nanoparticles obtained by chemical synthesis: a review. Arnaldoa [online]. 2024, vol.31, n.1, pp.171-185. Epub Apr 20, 2024. ISSN 1815-8242. http://dx.doi.org/10.22497/arnaldoa.311.31109.
The study and improvement of the antibacterial capacity of innovative compounds, such as nanoparticles, turns out to be of vital importance because bacteria are rapidly acquiring resistance to antibiotics. The objective of this research is to carry out a bibliographical review on the effect of silver nanoparticles obtained from different or diverse chemical syntheses applied to different groups of bacteria, silver nanoparticles have been effective against many groups of bacteria such as gram bacteria. positive and gram negative. Silver nanoparticles vary in morphology and size, which influences their antibacterial activity. Showing a better effect on gram negatives, possibly due to its thinner bacterial wall allowing nanoparticles or derived ions to pass through more easily and act at the membrane level or enter the cell where they can damage the respiratory chain, cause damage in proteins, lipids, nucleic acids among others. Likewise, on Staphylococcus aureus, the smaller the size, the greater the antibacterial activity was appreciated due to its easy entry and with respect to the morphology we can point out that the most frequent was the spherical one. Finally, it is concluded that the silver nanoparticles obtained by chemical synthesis have a high antibacterial activity.
Keywords : silver nanoparticles; size; morphology; characterization; reduction chemical synthesis; bacterial resistance; mechanism of action.