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Revista Medica Herediana

Print version ISSN 1018-130XOn-line version ISSN 1729-214X


BRAVO ZUNIGA, Jessica; LOZA MUNARRIZ, Reyner  and  FERRUFINO LLACH, Juan. IgA Nephropathy: a case report. Rev Med Hered [online]. 2005, vol.16, n.3, pp.223-227. ISSN 1018-130X.

IgA Nephropathy is an immune-mediated glomerulonephritis involving a heterogeneous group of patients with a variety of different clinical permutations.A 4-year-old girl with 2-month history of intermittent haematuria, without dysuria or increased frequency of micturition. On examination, she appeared fit and healthy; only with palpebral edema. Urine analysis showed microscopic haematuria (3+) and nephrotic proteinuria. Intravenous urography, and sonnografic study were normal. Her haemoglobin, white-cell count, blood urea and creatinine clearance were normal; the urinary protein excretion was 45mg/m2/h. C4 and C3 levels were within normal limits. In view of the duration of haematuria, a renal biopsy was performed. Thirteen glomeruli were present: all showed a diffuse increase in mesangial cells with thickening of the matrix and some necrosis zones. Immunofluorescent examination of the biopsy showed mesangial deposits of IgA and C3. The appearances were characteristic of IgA nephropathy (Rev Med Hered 2005;16:223-227).

Keywords : Haematuria; Ig A nephropathy; renal failure.

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