Resumen

PONCE, Freddy Liñán; LEIVA GOICOCHEA, Juan  y  CHAVEZ CORRALES, José. Systemic sclerosis sine scleroderma in a woman with centromere antinuclear antibodies, pulmonary and digestive involvement: Case report. Rev. Fac. Med. Hum. [online]. 2023, vol.23, n.3, pp.162-166.  Epub 21-Sep-2023. ISSN 1814-5469.  http://dx.doi.org/10.25176/rfmh.v23i3.5670.

Sine entities are rare in rheumatology. In progressive systemic sclerosis there is a variant of the limited cutaneous form called systemic sclerosis sine scleroderma, whose central feature is the lack of skin involvement, but visceral involvement is present. Positive anti-topoisomerase or anti-centromere antibodies confirm the diagnosis. We present the case of a 63-year-old woman with interstitial lung disease, intestinal transit involvement and Raynaud's phenomenon, with high titers of ANA with a centromeric pattern and positivity for anti-topoisomerase antibodies. When faced with a patient with Raynaud's phenomenon, visceral involvement and elevated ANA, specific antibodies should be requested for the diagnosis of systemic sclerosis in its sine variety.

Palabras clave : Systemic sclerosis; Raynaud's disease; antinuclear antibodies.

        · resumen en Español     · texto en Español | Inglés     · Español ( pdf ) | Inglés ( pdf )